Intraarticular triamcinolone hexacetonide, stanozolol, Hylan G-F 20 and platelet concentrate in a naturally occurring canine osteoarthritis model
نویسندگان
چکیده
منابع مشابه
Widespread somatosensory sensitivity in naturally occurring canine model of osteoarthritis
Osteoarthritis (OA)-associated pain is a leading cause of disability. Central sensitization (CS), as a result of OA, is recognized as an important facet of human patients' chronic pain and has been measured in people using quantitative sensory testing (QST) testing. The spontaneous canine OA model has been suggested as a good translational model, but CS has not been explored in this model. In t...
متن کاملManaging joint pain in osteoarthritis: safety and efficacy of hylan G-F 20
The use of intra-articular viscosupplementation in the nonoperative management of patients with osteoarthritis has become quite popular. Recent clinical data have demonstrated that the anti-inflammatory and chondroprotective actions of hyaluronic acid viscosupplementation reduce pain while improving patient function. We review the basic science and development of viscosupplementation and discus...
متن کامل[18-month observational study on efficacy of intraarticular hyaluronic acid (Hylan G-F 20) injections under ultrasound guidance in hip osteoarthritis].
OBJECTIVE To evaluate the efficacy and the tolerability of viscosupplementation (VS) with hyaluronic acid (Hylan GF 20) in a cohort of 36 patients affected by hip osteoarthritis through a 18 months follow-up. METHODS Viscosupplementation was performed with an anteriorsagittal approach, under ultrasound guidance. 36 patients were administered hyaluronic acid intraarticularly in the hip, with a...
متن کاملHylan G-F 20 was safe and effective in knee osteoarthritis and had a relatively low cost-utility ratio.
In patients with knee osteoarthritis (OA), what are the effectiveness, cost-effectiveness, and safety of hylan G-F 20 in addition to an appropriate care regimen? D e s i g n Randomized (allocation concealed*), un-blinded,* controlled trial with 1-year follow-up. P a t i e n t s 255 ambulatory patients with radiologically verified knee OA and a visual analogue scale (VAS) total pain score > 175 ...
متن کاملInitial evaluation of nighttime restlessness in a naturally occurring canine model of osteoarthritis pain
Chronic pain due to osteoarthritis (OA) can lead to significant disruption of sleep and increased restlessness. Our objective was to assess whether naturally occurring canine OA is associated with nighttime restlessness and so has potential as a model of OA-associated sleep disturbance. The study was designed as a two-part prospective masked, placebo-controlled study using client-owned dogs (Pa...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2021
ISSN: 2045-2322
DOI: 10.1038/s41598-021-82795-z